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Question

Chemistry Question on Organic Chemistry- Some Basic Principles and Techniques

Which technique among the following, is most appropriate in separation of a mixture of 100 mg of p-nitrophenol and picric acid?

A

Steam distillation

B

2-5 ft long column of silica gel

C

Sublimation

D

Preparative TLC (Thin Layer Chromatography)

Answer

Preparative TLC (Thin Layer Chromatography)

Explanation

Solution

Thin layer chromatography is a technique used to isolate non-volatile mixtures.
Hence, mixture of p-nitrophenol and Picric acid is separated by TLC.

So, the correct option is (D): Preparative TLC (Thin Layer Chromatography).