Question
Biochemistry Question on Immunological techniques
Which one or more of the following statements correctly describe(s) the addition of N-nucleotides during the rearrangement of the immunoglobulin heavy chain- encoding gene?
A
Addition of N-nucleotides is template encoded
B
N-nucleotides are added by terminal deoxynucleotidyl transferase
C
The added N-nucleotides are common in V-D and D-J junction
D
N-nucleotides are added by the DNA polymerase II.
Answer
N-nucleotides are added by terminal deoxynucleotidyl transferase
Explanation
Solution
The correct options are: (B): N-nucleotides are added by terminal deoxynucleotidyl transferase(C):The added N-nucleotides are common in V-D and D-J junction.