Question
Physical Pharmacy Question on Solubility
Which one of the following statement holds true for Passive Diffusion?
A
Greater the area and greater the thickness, faster is the diffusion
B
Rate of drug transfer is directly proportional to the concentration gradient between GI fluids and the blood compartment
C
Rate of transfer of ionised drug species is 3‐4 times the rate for unionised drug species
D
Greater the membrane/water partition coefficient of drug, slower is the absorption
Answer
Rate of drug transfer is directly proportional to the concentration gradient between GI fluids and the blood compartment
Explanation
Solution
The correct option is (B): Rate of drug transfer is directly proportional to the concentration gradient between GI fluids and the blood compartment