Question

Which one of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is as follows 5’AUCGAUCGAUCGAUCGAUCGAUCG AUCG 3’?

• A. 3’ UAGCUAGCUAGCUAGCUAGCUAGCUAGC 5’
• B. 5’ ATCGATCGATCGATCGATCGATCGATCG 3’
• C. 3’ ATCGATCGATCGATCGATCGATCGATCG 5
• D. 5’ UAGCUAGCUAGCUAGCUAGCUAGCUAGC 3’

Answer 1

Answer: (B)

5’ ATCGATCGATCGATCGATCGATCGATCG 3’

Answer 2

The sequence on the mRNA strand is read from the 5' end to the 3' end, and it forms a complementary sequence to the template DNA strand. To find the corresponding coding strand, you need to match the base pairs according to the rules of complementary base pairing:

mRNA: 5' AUCGAUCGAUCGAUCGAUCGAUCGAUCG 3'
DNA: 3' TAGCTAGCTAGCTAGCTAGCTAGCTAGC 5'

The coding strand is complementary to the template DNA strand. So, the correct sequence on the coding strand is:
5' ATCGATCGATCGATCGATCGATCGATCG 3'

The correct option is (B): 5’ ATCGATCGATCGATCGATCGATCGATCG 3’