Question
Biology Question on Biomolecules
Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain ?
A
Lipase
B
Exonuclease
C
Endonuclease
D
Protease
Answer
Endonuclease
Explanation
Solution
Endonucleases are enzymes that hydrolyze internal phosphodiester bonds in a polynucleotide chain, cleaving the DNA or RNA at specific locations within the molecule. Exonucleases, on the other hand, remove nucleotides from the ends of the molecule, not from internal positions. Lipases and proteases are not involved in nucleic acid hydrolysis; lipases are involved in lipid metabolism, and proteases are enzymes that cleave peptide bonds in proteins.
So, the correct option is (C): Endonuclease