Question
Question: Which one of the following esters is the most reactive for saponification?...
Which one of the following esters is the most reactive for saponification?
A
B
C
D
Answer
Explanation
Solution
Saponification is a base catalysed hydrolysis (SN2Th) reaction which is a sterically controlled reaction too. The least crowded ester around acyl carbon will be most reactive towards this reaction.