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Question

Pharmacy Question on Drugs

Which one is the correct statement about drug metabolism?

A

Phenobarbital and rifampin are inducers of CYP450

B

Cigarette smoking leads to decrease in the CYPIAI and CYPIA2 levels.

C

Cimetidine is the only H2 antagonist that induces CYP450.

D

17a-ethinyl oestradiol is non-mechanism based inhibitor of CYP450.

Answer

Phenobarbital and rifampin are inducers of CYP450

Explanation

Solution

The correct option is(A): Phenobarbital and rifampin are inducers of CYP450