Question

Which of the following will be oxidized by $HIO_4$?

• A. 1, 2 and 3
• B. 1, 3 and 4
• C. 1, 2 and 4
• D. 2, 3 and 4

Answer 1

Answer: (C)

1, 2 and 4

Answer 2

Explanation:
The characteristics property of periodic acid is the oxidative cleavage of bonds with oxidisable groups such as 1,2-diols, ∝-hydroxy carbonyl compounds, 1,2-diketones, etc.For two adjacent oxidisable groups, one molecule of reagent is used which oxidises ketones to carboxylic acids and alcohols are oxidised to aldehydes by HIO4.The reaction of given compounds with HIO4 can be shown as:1. It is 1, 2 diketones, thus undergoes oxidative cleavage, as given:2. It is ∝- hydroxy carbonyl compound, thus undergoes oxidative cleavage, as given:3. It is 1, 3 diol, thus will not undergo oxidative cleavage as given:4. It is 1,2 diol, thus undergoes oxidative cleavage.Hence, the correct option is (C).