Question

Which of the following statements is not correct?
A. Oxyntic cells are present in the mucosa of stomach and secrete HCL
B. Acini are present in the pancreas and secrete carboxypeptidase
C. Brunner’s glands are present in the submucosa of stomach and secrete pepsinogen.
D. Goblet cells are present in the mucosa of intestine and secrete mucus.

Answer 1

Oxyntic cells (also known as parietal cells) are present in the lining of the stomach which secretes gastric acid. Acini are present in the pancreas and secrete carboxypeptidase.

Complete step by step answer:
Parietal cells (also known as oxyntic cells) are epithelial cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and cardia regions of the stomach.
-Carboxypeptidase called pancreatic exopeptidase as it hydrolyzes peptide bonds of C terminal residues with the aromatic or aliphatic side chains. Carboxypeptidases are secreted from pancreatic acinar cells known as zymogens that are activated by the trypsin in the intestines.
-Goblet cells are glandular and simple columnar cells that are present in the epithelia of most organisms. Their name goblet is given because of their shape, as they are similar to a goblet, with their narrow bases and having a wide apex. They are responsible for the secretion of mucus.
-Brunner’s glands are present in the submucosa of the small intestine rather than the stomach and they secrete an alkaline fluid rich in mucin which protects the duodenal surface of the small intestine from the action of the acidic chime. The secretion of the brunner gland helps principally to protect the intestinal walls from gastric juices.
So, the correct answer is option C.

Note: The main component of gastric juice is hydrochloric acid, it is the secretory product of the parietal, or oxyntic cell. The capacity of the stomach to secrete HCl is mainly dependent on the number of parietal cells.