Question

Which of the following statement regarding the structure of proinsulin and mature insulin are not correct?

(i) Proinsulin is made up of three polypeptide chain – A, B and C.

(ii) C- Polypeptide chain with 33 amino acids is removed prior to insulin formation

(iii) Mature insulin is made up of 51 amino acids arranged in two polypeptide chains – A and B

(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids.

(v) Polypeptide chains A and B are interconnected by only one S – S linkage.

• A. (i) and (ii)
• B. (iv) and (v)
• C. (iii) and (iv)
• D. (iii), (iv) and (v)

Answer 1

Answer: (B)

(iv) and (v)