Question

Which of the following sets of syndromes shows 47 chromosomes in their genetic makeup?
A. Turner’s syndrome, Edward’s syndrome, Klinefelter's syndrome
B. Klinefelter's syndrome, Turner’s syndrome, Patau’s syndrome
C. Down’s syndrome, Patau’s syndrome, Edward’s syndrome
D. All the above

Answer 1

The genetic disorder can lead to developmental delays and changes the genetic makeup of an organism. It is usually caused by an extra copy of the chromosome in cells. It mainly occurs due to nondisjunction that occurs at the time of cell division.

Complete answer: Down’s syndrome is a genetic syndrome caused by an abnormal cell division that results in a full or partial copy of chromosome number 21. This extra genetic material causes change in the developmental features and physical changes. It is also known as trisomy 21.
Patau’s syndrome is a chromosomal abnormality in which all cells or some cells contain extra chromosomal material at chromosome 13. The extra genetic material disrupts normal development, which can lead to multiple organ defects.
Edwards syndrome or trisomy E is a genetic disorder caused by the extra chromosomal material at chromosome. Most of the people with this syndrome die in the early fetal stages. People who survive show serious side effects and usually live only for a shorter period.
Hence, the correct answer is option C.

Note: The disorders that cause an increase in the chromosome number is known as trisomy. Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene. The term "karyotype" refers to the full set of chromosomes from an individual; this can be compared to a "normal" karyotype for the species via genetic testing.