Question

Which of the following reactions is appropriate for converting acetamide to methanamine ?

• A. Hoffmann hypobromamide reaction
• B. Stephen's reaction
• C. Gabriel phthalimide synthesis
• D. Carbylamine reaction

Answer 1

Answer: (A)

Hoffmann hypobromamide reaction

Answer 2

$CH _{3}- \overset{\underset{||}{O}}{C} - NH _{2}+ Br _{2}+4 NaOH \stackrel{\Delta}{\longrightarrow} CH _{3}- NH _{2}+2 NaBr + Na _{2} CO _{3}+3 H _{2} O$

It is called Hoffman bromamide reaction.