Question
Question: Which of the following is not true about drug receptors? A. Receptor proteins are embedded in the ...
Which of the following is not true about drug receptors?
A. Receptor proteins are embedded in the cell membrane.
B. The chemical known as chemical messengers are received at the binding sites of receptors.
C. The receptors show selectively for one chemical messenger over the other.
D. Receptor protein is decomposed and destroyed after removal of chemical messenger.
Solution
A receptor is a macromolecule found in the cell membrane or within the cell that binds a ligand directly (chemically) (drug). A drug's ability to bind to a receptor is determined by the types of chemical bonds that can be formed between the drug and the receptor. The degree of affinity of ligand to receptor is determined by the strength of chemical bonds (covalent, ionic, hydrogen, hydrophobic).
Complete step by step answer:
A receptor is a macromolecule found in the cell membrane or within the cell that binds a ligand directly (chemically) (drug). A drug's ability to bind to a receptor is determined by the types of chemical bonds that can be formed between the drug and the receptor. The degree of affinity of ligand to receptor is determined by the strength of chemical bonds (covalent, ionic, hydrogen, hydrophobic).
Agonists and antagonists are two types of ligands (drugs) that bind receptors. Since agonists trigger biological responses as a consequence of receptor–ligand interactions, they are efficacious. Antibodies, on the other hand, had no biological function despite binding to their receptor.
Receptors have two essential properties: they bind drugs (ligands) with a high affinity and then transduce a signal to induce a biological reaction after they bind a drug. Receptor regains its structure and shape after removal of the chemical messenger.
Hence, option D is the wrong statement.
Therefore, the correct answer is, ‘Option D’.
Note: Receptors have two essential properties: they bind drugs (ligands) with a high affinity and then transduce a signal to induce a biological reaction after they bind a drug. Receptor regains its structure and shape after removal of the chemical messenger.