Question

Which of the following immune responses is responsible for rejection of kidney graft?
A. Auto-immune response
B. Humoral immune response
C. Inflammatory immune response
D. Cell-mediated immune response

Answer 1

Rejection is an adaptive immune response by cell mediated immunity (T-cell mediated), includes programmed cell death as well as by humoral immunity (B- Cell mediated) includes antibody secretion by B-cells and this immune action is joined by phagocytes and soluble immune proteins which are components of innate immunity. Organ transplant rejection is performed by cellular immunity.

Complete answer:
An animal's presentation to the antigens of an alternate individual from the equivalent or comparable species is allostimulation, and the tissue is allogenic. Relocated organs are frequently gained from a corpse (normally a host who had capitulated to injury), whose tissues had just continued ischemia or aggravation.
Dendritic cells (DCs), which are the essential antigen-introducing cells (APCs), of the benefactor tissue move to the beneficiary's fringe lymphoid tissue (lymphoid follicles and lymph nodes), and present the contributor's self peptides to the beneficiary's lymphocytes (insusceptible cells dwelling in lymphoid tissues). Lymphocytes incorporate two classes that establish adaptive immunity, additionally called specific immunity. Lymphocytes of adaptive immunity include the subclasses helper T cells and killer T cells, and B cells.
The beneficiary's assistant T cells facilitate adaptive immunity coordinated at the benefactor's self peptides or at the donor's Major histocompatibility complex particles, or at both.
Transplantation is the demonstration of moving cells, tissues, or organs starting with one site then onto the next, regularly between different individuals. The malfunction of an organ framework can be remedied with transplantation of an organ (eg, kidney, liver, heart, lung, or pancreas) from a giver. Nonetheless, the insusceptible framework remains the most considerable boundary to transplantation as a standard clinical treatment.

So, (D) is the correct answer.

Note:
The immunity framework has created strong and successful components to battle unfamiliar agents. These components are additionally engaged with the dismissal of relocated organs, which are perceived as unfamiliar by the receiver's immune system.