Question
Question: Which of the following does not play a role in blood coagulation? A. Vitamin K B. Vitamin D. C....
Which of the following does not play a role in blood coagulation?
A. Vitamin K
B. Vitamin D.
C. Calcium ions
D. Fibrinogen.
Solution
Blood coagulation is crucial process. When a person suffers an injury, it is first life-saving process to survive an injury, in which series of reaction take place and number of factor are involved to carry out the coagulation of blood or clotting of blood. Disorder in coagulation can cause or act as disease.
Complete answer:
Blood clotting occurs when subendothelial space initiates the two different processes, such as change in the platelets and exposure of special tissue to plasma factor VII, that ultimately leads to the formation of cross linked fibrin. Platelets form a plug at the site of injury that act as primary hemostasis and then additional coagulation factor forms the fibrin strands that strengthen the platelet plug which act as secondary hemostasis.
Vitamin K involved in the formation of blood clotting process, it acts as coenzyme for the carboxylation process and act as activation of some enzymes is coagulation of cascade.
Calcium ions play an important role in the blood coagulation, they are involved in conversion of prothrombin to thrombin, Calcium ion leads in the activation of a protein called factor X.
Fibrinogen is the soluble plasma protein or known as factor-I, which is made in liver, it is one of the 13 coagulation factor, which help in the formation of cascade formation in blood clotting
Vitamin-D is stored in fact in tissue and is formed by taking sunlight and required for strong bones, so it does not play any role in blood coagulation.
So, the correct option is D.
Note: Coagulation defect may lead to certain kinds of cause like hemorrhage or thrombosis. Some of them are named as platelet disorders, which may be inborn or acquired, example:- Glanzmann’s thrombasthenia, von willebrand disease. One of the most famous hereditary diseases related to blood coagulation is hemophilia in which a person suffers lack of blood clotting factor formation.