Question
Question: Which of the following compounds is least reactive in the nucleophilic aromatic substitution reactio...
Which of the following compounds is least reactive in the nucleophilic aromatic substitution reaction with NaOH?
A
p-nitrofluorobenzene
B
p-nitrochlorobenzene
C
p-nitrobromobenzene
D
p-nitroiodobenzene
Answer
p-nitroiodobenzene
Explanation
Solution
Because rate of SN2 Ar is Ar–F > Ar–Cl > Ar–Br > Ar–I.