Question

Which is the correct sequence of events of inflammation or phagocytosis?
(a)Vasodilation → Diapedesis → Adhesion → Chemotaxis → Phagocytosis
(b)Vasodilation → Adhesion → Emigration → Chemotaxis → Diapedesis → Phagocytosis
(c)Adhesion → Vasodilation → Diapedesis → Chemotaxis → Phagocytosis
(d)Vasodilation→Adhesion→Diapedesis→Chemotaxis→Phagocytosis

Answer 1

Phagocytosis is that the primary method employed by the body to get rid of free microorganisms within the blood and tissue fluids. An inflammatory response to injury and/or infection allows phagocytes to go away from the bloodstream, enter the tissue, and move to the location of infection or injury.

Complete answer:
Vasodilation is 1 of the earliest manifestations of acute inflammation. It refers to the widening of the blood vessels. Then leucocyte adheres to the vascular endothelium. The changes in the structure of microvascular emigrate the leucocytes from microcirculation followed by chemotaxis, whereby the cells move in response to chemical signals and the movement is known as diapedesis. Lastly is phagocytosis where the cell (or the phagocyte) engulfs a solid particle to form an internal vesicle known as phagosome,
So, the correct answer is, ‘Vasodilation → Adhesion → Emigration → Chemotaxis → Diapedesis → Phagocytosis.’

Note: The series of events within the process of inflammation are:
-Vasodilation: results in greater blood flow to the area of inflammation, leading to redness and warmth.
-Vascular permeability: endothelial cells start leaking from either direct endothelial cell injury or via chemical mediators.
-Exudation: In this, there occurs the escaping of the fluid, proteins, red blood cells, and white blood cells go after from the intravascular space as a result of increased pressure extravascularly and increased hydrostatic pressure intravascularly
-Vascular stasis: In this step, slowing of the blood within the bloodstream along with the vasodilation and fluid exudation to permit chemical mediators and inflammatory cells to gather and respond to the given stimulus.