Question

Which is not the symptom of Cushing's syndrome, out of the following?
A. Increased blood sugar level
B. Decrease in weight
C. Rise in blood pressure
D. Rise in blood volume

Answer 1

Cushing's syndrome - Cushing's syndrome is a condition that occurs for the high cortisol levels for a long time. The most common reason is the use of steroid drugs. But it can also arise from overproduction of cortisol hormone by the adrenal glands. Signs are a rounded face, a fatty lump between the shoulders and pink or purple stretch marks. Treatment options consist of surgery,decreasing steroid usage, radiation and medication.

Complete answer:
Cushing's syndrome is a disorder related to the adrenal glands. It is initiated due to hypersecretion or over secretion of adrenal hormone called Cortisol by adrenal glands in the body. As cortisol controls carbohydrate metabolism, overproduction of this causes an increase of blood sugar level. Blood pressure also increases due to the same reason. Other symptoms of this syndrome are weight gain, increase in blood volume, muscle weakness, fatigue, fatty hump between the shoulders etc.

So, Option B ‘Decrease in weight’ is the correct option.

Additional Information:
Option A – Increased blood sugar level: In the Cushing's syndrome blood sugar level gets increased as the over secreted cortisol hormone secreted by the adrenal gland controls the carbohydrate metabolism and increases the sugar level in blood. So, the information is correct.
Hence, the option A ‘Increased blood sugar level’ is not the correct option.
Option C – Rise in blood pressure: In the Cushing's syndrome Blood pressure level is also increased. It is also a symptom of Cushing's syndrome. So, the information is correct.
Hence, the option C ‘Rise in blood pressure’ is not the correct option.
Option D – Rise in blood volume:In the Cushing's syndrome Blood volume is also increased. It is also a symptom of Cushing's syndrome. So, the information is correct.
Hence, the option D ‘Rise in blood volume’ is not the correct option.

Note:
Most of the cases of Cushing's syndrome can be cured. However it may take some time for the indications to ease up. This syndrome is more common in women than in men. It is relatively common in people aged $25 - 40$.
Cushing disease is a particular type of Cushing syndrome. It happens when the body starts making too much cortisol as a result of a pituitary tumour. Cushing disease is the most communal form of endogenous Cushing syndrome and makes up about $70\%$ of Cushing syndrome cases.