Question

Which are III and IV factors responsible for blood clotting?
A. Prothrombin, Calcium
B. Thromboplastin, Proaccelerin
C. Thromboplastin, Proconvertin
D. Prothrombin, Antihemophilic globulin (AHG)

Answer 1

As we all know that blood clotting or coagulation is a series of chemical reactions that culminates in the formation of fibrin threads and involves several factors responsible for conversion of plasma protein fibrinogen to insoluble fibrin.

Complete answer:
As we all know that the process of blood clotting or coagulation is a series of chemical reactions that culminates in the formation of fibrin threads and involves several factors responsible for the process.
These factors are called clotting factors and include Calcium ions, several inactive enzymes that are synthesised by hepatocytes and released into the bloodstream and various other molecules associated with platelets or released by damaged tissues.
The fundamental reaction in the clotting of blood is the conversion of soluble plasma protein fibrinogen to insoluble fibrin catalysed by the enzyme thrombin at the site of injury.
Prothrombinase is responsible for conversion of prothrombin into the enzyme thrombin.
There are a total of twelve clotting factors which includes: Factor I is called Fibrinogen, found in Liver along with Factor II which is called Prothrombin.
Factor III is called tissue Thromboplastin and it is found mainly at the damaged tissues and platelets.
Factor IV is Calcium ions and main sources of this factors include diet, bones and platelets.
Factor V is Proaccelerin found in Liver and platelets.
Factor VII is called Proconvertin again the source is Liver, along with Factor VIII which is Anti haemophilic factor-A, Factor IX called Christmas factor or plasma thromboplastin or Anti haemophilic factor-B, Factor X which is called Stuart factor, thrombokinase, Factor XI is plasma thromboplastin antecedent or Anti haemophilic factor –C, Factor XII is called Hageman factor or glass factor or Anti haemophilic factor –D and XIII Factor called Fibrin stabilizing factor or fibrinase.
There is no factor VI.

Hence from the above explanation we can say that the correct answer is (C).

Note: Related facts: Haemophilia is an inherited bleeding disorder where blood clotting property is lost due to the absence of clotting factors VIII in Haemophilia A and IX factor in Haemophilia B. Heparin is considered an anticoagulant, it prevents clotting or blood.