Question
Question: Which antibody is present in colostrum?...
Which antibody is present in colostrum?
Solution
Colostrum is a breast's milky fluid produced by females of humans, cows, and other mammals before breast milk is released. It is very nutritious, it promotes growth and health in infants. Colostrum has a high amount of bioactive compounds compared to mature milk to give the newborn the best start to life.
Complete answer:
Colostrum contains antibodies to protect the newborn against disease and infections. It also has growth factors and other bioactive properties that help to activate a newborn's immune system, start gut function and help in building a healthy gut microbiome in the first few days of life.
The bioactive form found in Colostrum is especially essential for a newborn's health, growth and vitality.
Colostrum has immune cells (as lymphocytes) and many antibodies such as IgA, IgG, and IgM. Among these antibodies the most predominant one is IgG, it functions to identify and demolish pathogens found within the bloodstream as well as other parts of the body.
Other components of Colostrum include lactoferrin, lysozyme, lactoperoxidase,proline-rich polypeptides, these components help in building innate immunity.
A number of cytokines are also present in Colostrum. Cytokines are small messenger peptides that control the functioning of the immune system e.g. interleukins, tumor necrosis factor, chemokines, etc.
The growth factors present in Colostrum are insulin like growth factor 1 (IGF-1), and 2, transforming growth factor alpha, beta 1 and beta 2, fibroblasts growth factors, epidermal growth factor,etc.
Colostrum also has a mild laxative effect, encouraging the passing of the baby's first stool, this clears excess bilirubin, a waste product of dead red blood cells which is produced in large quantities at birth due to blood volume reduction from the infant's body and helps prevent jaundice.
So,the antibody IgG is the most predominant antibody found among others.
Note:
Other than antibody IgG antibody IgA and IgM also present in Colostrum but the most predominant is IgG. Bovine Colostrum is similar to human Colostrum rich in vitamins, minerals, fats, carbohydrates, etc so bovine Colostrum supplements have become popular in recent years as it helps to promote immunity, fight infection and improve gut health, for this Colostrum from cows is pasteurized and dried into pills or into powders for easier consumption.