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Question

Biology Question on Molecular Basis of Inheritance

Which antibiotic inhibits interaction between t-RNA and m-RNA during bacterial protein synthesis ?

A

Erythromycin

B

Neomycin

C

Streptomycin

D

Tetracycline

Answer

Tetracycline

Explanation

Solution

Tetracycline disrupts the binding of tRNA molecules carrying amino acids to the mRNA-ribosome complex, thereby preventing the incorporation of amino acids into the developing polypeptide chain. Streptomycin, on the other hand, disrupts the initial stages of protein synthesis by altering the conformation of the 30S subunit within the 70S prokaryotic ribosome. Erythromycin, meanwhile, interacts with the 50S subunit of the 70S prokaryotic ribosome.

so, the correct option is (D): Tetracycline