Question
Question: Where is Insulin produced?...
Where is Insulin produced?
Solution
Insulin is a peptide hormone generated by the pancreas and is the body's primary anabolic hormone. It controls carbohydrate, fat, and protein metabolism by increasing glucose absorption from the blood into the liver, fat, and skeletal muscle cells. In these tissues, ingested glucose is converted to glycogen or lipids (triglycerides) by glycogenesis or lipogenesis, or both in the case of the liver.
Complete answer:
Insulin is produced by the beta cells of the islets of langerhans present in the human pancreas.
Insulin is produced in response to rising levels of glucose in the bloodstream.
The level of insulin in blood increases as soon as an individual has taken his/her meal, as after meals the level of blood glucose in blood increases as a result of digestion of
carbohydrates.
Additional information:
The pancreas is a retroperitoneal organ with two morphologically different tissues, the exocrine and endocrine pancreas, which determine its varying function.
The exocrine part of the pancreas produces pancreatic juice which consists of various digestive enzymes that helps in digesting the food in the small intestine of the alimentary canal. The endocrine pancreas is divided into Langerhans islets, which include five cell subtypes namely α,β,δ, ε, and PP cells that produce glucagon, insulin, somatostatin, ghrelin, and pancreatic polypeptide, respectively. Only 2% of the mature pancreatic mass is made up of islet cells.
Note:
Insulin works by increasing the absorption of glucose from the circulation through cell membranes and into the body's cells, thus removing glucose from the bloodstream. Once within the cells, glucose is either utilized as energy to power the cells' many functions or stored as glycogen in the liver or muscle cells. As a result, the blood glucose level drops, causing the pancreas to turn off the insulin secretion.