Question

Where does Urea formation take place in the body?

Answer 1

Urea is an excretory waste material excreted by our body in urine .Urea is the major end product of nitrogen metabolism in humans. Urea is produced in our body with the process of urea cycle.

Complete answer:
Urea production:-
Urea formation takes place in the hepatocytes of the liver and then it is released into the bloodstream.
Then the kidney filters that urea containing blood and excrete out urea from the body in urine.
The urea cycle is a biochemical reaction that produces urea from ammonia.
As ammonia is highly toxic material so in order to convert ammonia to a less toxic material i.e. urea, urea cycle is important.
This cycle was first discovered by Hans Krebs and Kurt Henseleit in 1932 but it was later described in more detail by Ratner and Cohen.
So, from the above discussion it is clear that the Urea formation takes place in Liver.

Note: Remember to keep in mind that those organisms that cannot easily or safely excrete nitrogen as ammonia, they convert it into less toxic substance i.e. urea.