Question

What would be the molar concentration of human DNA in a human cell?

Answer 1

DNA is deoxyribonucleic acid. All the 23 pair chromosomes carry DNA. These are double-stranded coiled helices. These have two polypeptide strands.

Complete answer:
Human genome is a set of nucleic acids sequence in the case of humans which is encoded as DNA with all 23 pairs of chromosomes in cell nuclei. DNA is deoxyribonucleic acid. It is composed of two polynucleotide chains. These coils around each other forming a helix. It carries information about the genetic development, growth and functioning of an individual. These also carry the physical trait genes from the parents.
Normal Weight of a single pair in a DNA strand is 650 daltons.
Weight of 1 dalton is $1.66 \times {10^{24}}$ gms.
This is equivalent to carbon -12 atoms $\dfrac{1}{{12}}$th mass.
Human genome in total has $3.3 \times {10^9}$ pairs.
The molecular weight of DNA = no of pairs$\times 650$Daltons.
This totals as ($3.3 \times {10^9}$)$\times 650$=$2.15 \times {10^{12}}$daltons which equal to 3.5 picograms.
DNA with respect to moles—
One mole is the Avogadro number.
Moles = $3.3 \times 10^9$ / avogadro number
$3.3 \times {10^9}$ $\times 6 \times {10^{23}}$
=5.5 femtomoles of DNA.
In respect to molarity
The cell volume = $5 \times {10^{ - 12}}$ i.e. 5 picolitre
Molarity of DNA in a cell = $5.5 \times {10^{ - 15}} \times 5 \times {10^{ - 12}}$=0.0011 M

Note: Molarity is defined as no of moles of solute per litre of solution.
— Human genome is a complete set of nucleic acids sequence in humans which is encoded as DNA with all 23 pairs of chromosomes in cell nuclei. DNA is deoxyribonucleic acid. It is composed of two polynucleotide chains. These coils around each other forming a helix.