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Question: What is the mode of inheritance?...

What is the mode of inheritance?

Explanation

Solution

Inheritance is a process by which genetic information is passed from a parent to the offspring. Hence, members of the same family possess the same characteristics. It happens either via asexual reproduction or sexual reproduction. Genetics is a branch, which deals with the study of heredity.
It is the transmission of traits, information and genomic sequences to the children.

Complete answer
Mode of inheritance is a manner by which a genetic trait or a genetic disorder is passed on from one generation to subsequent generations.
There are basically five modes of inheritance. They are as follows:
1. Autosomal recessive
2. Autosomal dominant
3. X-linked recessive
4. X-linked dominant
5. Mitochondrial

1. Autosomal dominant: It indicates genetic conditions, which occur when a mutation is present in a single copy of a given gene (provided the person is heterozygous).
Example for autosomal dominant genetic disorder is hereditary breast cancer syndrome, which is related with pathogenic variants BRCA11, BRCA22 and PALB22

2. Autosomal recessive: It takes place only when the mutation is present in both copies of a given gene. Here, the person is homozygous for the mutation. Examples are cystic fibrosis and sickle cell anemia.

3. X-linked dominant: It hints at genetic conditions, which are associated with mutations in the X chromosome only. A single copy of mutation is sufficient to cause disease in females (two X chromosomes) and male (one X chromosomes). During some situations, absence of a functional gene can cause death in male.

4. X-linked recessive: It is also associated with mutations in the X chromosome. A female, who carries a mutation in a gene, possessing a normal gene in another X chromosome is usually unaffected. But the male carrying a mutation is affected as he carries only one X chromosome

5. Mitochondrial: Mitochondria possess their own genetic material apart from the genetic material present in the nucleus. Mitochondria and mitochondrial DNA are passed from mother to children.

Note:
First degree relatives include siblings, parents and offspring. They share 50%50\% of DNA. Second degree relatives include uncles, aunts, grandchildren, grandparents, nephews, nieces and half siblings. They share 25%25\% of DNA. Third degree relatives include first cousins. They share 12.5%12.5\% of DNA. Pedigree is a term for the graphic illustration of family history, where relationships between family members are displayed.