Question
Pharmacology Question on Chemotherapy
What is the mechanism of action of Methotrexate
A
Inhibition of Dihydrofolate reductase
B
Inhibits cell replication by acting on G phase of cell cycle
C
Inhibits pyrimidine synthesis
D
Inhibits Thymidylate synthase
Answer
Inhibition of Dihydrofolate reductase
Explanation
Solution
The correct option is (A) :Inhibition of Dihydrofolate reductase