Question
Question: What is the major product in the following reaction?  and E2 (bimolecular elimination).
E2 mechanism is a one step mechanism. In alkyl halides the carbon-halogen and carbon-hydrogen bond breaks in a single step forming a double bond. It is a second order reaction in which the rate depends upon both substrate and eliminating agent. The base usually abstracts the proton from the substrate and the leaving group (halogen mostly) leaves forming double bonded organic compounds. The important point to note is that the leaving group and the β−H (that the base abstracts) should be antiperiplanar to each other.
The most common mechanism for dehydrohalogenation is the E2 mechanism.
Now, coming to our question;
The given reaction is a dehydrohalogenation. It undergoes elimination via E2 mechanism. Where bromide (Br) is a leaving group and the base present (NaOMe) will abstract the β−H forming 3,3−Dimethylcyclohexene .
We can clearly see that the leaving group bromide and the β−H are antiperiplanar. Thus, the reaction takes place via the E2 mechanism.
Note:
We should know about the E1 mechanism as well. It takes place via two steps. There is a formation of carbocation as an intermediate in the E1 mechanism. The reaction rate is proportional to only the concentration of substrate. It exhibits first-order kinetics. E1 mechanism shows similar features as the SN1 reaction.