Question
Pharmaceutical Analysis Question on Chromatography and Its Principles
What is the main different between HPLC and UPLC
A
HPLC is reverse-phase whereas UPLC in normal-phase
B
UPLC employs smaller stationary-phase particle size
C
HPLC and UPLC employ different mobile phase
D
HPLC and UPLC employ different detection methods
Answer
UPLC employs smaller stationary-phase particle size
Explanation
Solution
The correct option is (B) : UPLC employs smaller stationary-phase particle size