Question
Question: What is the function of fibrinogen in the blood?...
What is the function of fibrinogen in the blood?
Solution
Blood contains both fibrinogen (Fibrin) and platelets. These are vital in the maintenance of blood quality and the transmission of metabolic activities in the body, and they work in diverse ways. They are also very little in size.
Fibrinogen (a soluble protein) is a component of human blood that is transformed into Fibrin (an insoluble protein) during the healing of any wound.
Complete answer:
The synthesis of fibrin, which binds platelets and certain plasma proteins in a hemostatic plug, is fibrinogen's main physiological function. The network entraps huge numbers of erythrocytes and leukocytes under pathological circumstances, generating a thrombus that can obstruct a blood channel.
Fibrinogen is a protein that is required for normal blood clot formation. It is a clotting factor (factor I). Fibrinogen can be assessed using two different tests. A fibrinogen activity test determines how effective fibrinogen is at assisting in the formation of a blood clot.
Fibrinogen is a characteristic acute phase reactant in that it causes a significant increase in hepatic expression and circulating protein in response to inflammatory stimuli.
Note:
Fibrin is an insoluble protein that is created in response to any bleeding in the body and is recognised to be a major component of blood clotting. It's also extremely tough, with lengthy fibrous chains. These chains, in turn, are made up of fibrinogen, a soluble protein found in blood plasma. Fibrinogen is transformed to fibrin by the activity of an enzyme called thrombin, which is a clotting enzyme, at the site of damage or bleeding.
Fibrin molecules bind together to form long fibrin threads. These lengthy threads entangle platelets, causing a spongy mass to form that hardens after a short time. Fibrin stabilising factor is the chemical that controls the hardening process.