Question
Biology Question on Principles of Inheritance and Variation
What is point mutation? Give one example.
Answer
Point mutation is a change in a single base pair of DNA by substitution deletion or insertion of a single nitrogenous base. An example of point mutation is sickle cell anaemia. It involves mutation in a single base pair in the beta-globin chain of haemoglobin pigment of the blood. Glutamic acid in short arm of chromosome II gets replaced with valine at the sixth position.