Question

What is false about tRNA?
A. It binds with an amino acid at 5' end.
B. It has five base pairs stem
C. It has anticodon at one end which recognizes the codon on m-RNA
D. It looks like clover leaf in the two dimensional structure

Answer 1

Transfer RNA or tRNA, is one of the types of a nucleic acid family known as ribonucleic acid (RNA). The function of tRNA molecules is to decode a messenger RNA (mRNA) that helps to translate genes and transfer into a sequence of proteins.

Complete answer:
The tRNA molecule has a distinctive folded two dimensional structure with three hairpin loops that looks like cloverleaf.
The primary structure of tRNA contains the modified bases; dihydrouridine, ribothymidine, pseudouridine and inosine.
The amino acid binds with the sequence of CCA tail (cytosine-cytosine-adenine) at the 3' end of the tRNA molecule.

The cloverleaf molecular structure of tRNA, being the shape of a three-leafed clover, is composed of three characteristic loops such as anticodon, a D-arm and a T-arm.
As shown in the given figure above, the D arm is the loop closest to the 5' end and it often contains dihydrouridine bases.
The loop that contains the sequence of thymine-pseudouridine-cytosine lying closest to the 3' end is called the T arm.
The anticodon arm is a 5-bp stem whose loop found on the bottom of the cloverleaf structure contains the anticodon. The primary function of anticodon in t-RNA is to recognize and decode m-RNA codons

Hence, the correct answer is option (A).

Note: The molecules of Transfer RNAs or tRNAs act as temporary carriers between nucleotide and amino acid sequences. Its primary function is to bring up the appropriate amino acids to the ribosome by decoding the nucleotide sequence of the messenger RNA (mRNA). In this way, they act as the intermediaries in order to synthesize a protein from an mRNA molecule.