Question

What is factor 8 in blood clotting?

Answer 1

Blood clotting is the process that prevents blood loss from the body during wounds and injuries. It is a natural process that helps to maintain the level of blood by preventing blood loss.

Complete answer:
Whenever we get injured, the blood starts coming out of the wound and blood vessels. But after some time, it stops naturally by the formation of a clot or cap over the wound or vessel. It is called blood clotting. Blood clotting is also called coagulation. The process of coagulation starts when some tissue is injured and bleeding is started. Injured tissue releases a clotting factor that stimulates extrinsic and intrinsic.

The coagulation factors are listed in a chronological sequence of discovery. Although there are 13 numbers, there are only 12 elements. Factor VI was later shown to be a component of another factor. Coagulation factors and their common names are as follows: Fibrinogen, Prothrombin, Tissue thromboplastin (tissue factor), etc.

Hepatocytes are responsible for the vast majority of clotting factors produced. Hepatocytes are responsible for producing clotting factors XIII, XII, XI, X, X, IX, VII, V, II, and I in the body. Endothelial cells produce clotting factors VIII (antihemophilic factor A) and III (tissue factor), whereas plasma contains clotting factor IV (calcium ion). Factor V is produced in part by megakaryocytes.
Factor VIII (FVIII) is an essential blood-clotting protein, also known as an anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a recessive X attached coagulation disorder. Factor VIII occurs in liver endothelial cells and sinusoidal cells outer of the liver all over the body.
Hemophilia A is the usual kind of hemophilia and it occurs due to the shortage in factor VIII.

Note:
Hemophilia A is the most intense bleeding disorder. Blood doesn't clot in the proper way in hemophilia A. This causes a person in danger of uncontrolled blood loss. In normal conditions, some proteins, like factor VIII, come together to produce blood clots and instantly prevent blood loss.