Question

What is diapedesis?
A. A kind of amoeboid movement
B. Process of coming out of WBC through the capillary wall to fight against foreign microorganisms
C. A type of locomotion found in Hydra
D. The process of filtration of urea in kidney

Answer 1

Extravasation of white blood cells (diapedesis – displacement of cells through the intact blood vessel wall) is the transfer of leukocytes out of systemic circulation and to the
site of the wound injury or infection.

Complete answer: Diapedesis is reminiscent of an innate immune response involving the recruitment of nonspecific leukocytes. Monocytes use this mechanism in the absence of
disease or tissue damage during the production of macrophages. White blood cells perform almost all of their job in tissues. Features include phagocytes of foreign particles, antibody creation, secretion of inflammation reaction stimuli (histamine and heparin), and dilution of histamine. In specific, leukocytes are involved in the defence of the organism and defend it from infection by stimulating or hindering inflammatory reactions. Leukocytes use blood as just a form of transport to invade the body tissues. That being said, diapedesis remains the least understood but important aspect in the infiltration of leukocyte tissue. Diapedesis is probably to be regulated by molecular structure interactions and communicating cross-conversations between leukocytes and endothelial that continue to be clearly documented.
So, the correct option is (B)
Additional Information:
Leukocyte adhesion deficiency (LAD) is a genetic defect connected with a defect in the mechanism of leakage of leukocytes caused by a faulty integrin β2 chain. This reduces the stability of leukocytes to avoid and experience diapedesis. People with LAD have recurrent infectious diseases and delayed wound healing. Neutrophilia is a trademark of LAD. In deadly diseases such as sepsis, leukocyte extravasation begins an unpredictable stage where white cells white blood cells begin to degrade host tissues at exponential levels, claiming lives. Neutrophil malfunction is usually caused by some kind of infection that can cause pathogen-associated molecular patterns (PAMPs). As the extravasation of leukocytes strengthens, more tissues are harmed by neutrophils that emit oxygen radicals and proteolytic enzymes.

Note: Diapedesis seems to be the squeezing action of the WBC at the site of infection. It can be
specified as the passage of blood, and any of its components, through the intact lining of the blood vessels. WBC also defined as leukocytes, are immune cells that are interested in the defence of the body against infectious diseases and foreign invaders.