Question

What is denaturation of protein and name the two diseases caused due to deficiency of protein?

Answer 1

In the given question the first important concept is regarding the term of denaturation of protein. Now this is the breakage process of many of the weak linkages or bonds like hydrogen bonds(the ones with low enthalpy change), within a protein molecule that are also responsible for the highly ordered structure of the protein molecule in its naturally available state. And the two diseases are Marasmus and Kwashiorkor.

Complete answer: Denaturation (in biology) is a process where the molecular structure of a protein is modified. It involves the breakage process of many of the weak linkages or bonds like hydrogen bonds(the ones with low enthalpy change), within a protein molecule that are also responsible for the highly ordered structure of the protein molecule in its naturally available state.
Whereas according to the chemistry terms, Denaturation is the process where due to the change in pH, temperature or the presence of a specific salt or chemical agent, the complex structure of the protein is disrupted (altered). Due to this the protein loses its biological activity.
Two common diseases caused because of the deficiency of the protein are Marasmus and Kwashiorkor.

Note:
Proteins or Polypeptides are polymers of amino acids. A protein is created by ribosomes that "read" RNA that is encoded by codons in the gene and assemble the requisite amino acid combination from the genetic instruction, in a process known as translation. The newly created protein strand then undergoes posttranslational modification.