Question

What does it mean for a gene to be highly conserved?

Answer 1

The basic physical and practical unit of heredity is the gene. DNA is what makes up qualities. A few characteristics serve as instructions for the development of proteins, which are atoms. Nonetheless, certain attributes do not code for proteins.

Complete answer:
A gene that has essentially remained unchanged throughout evolution. The conservation of a gene indicates that it is unique and essential: there is no extra copy of that gene with which evolution can experiment, and changes in the gene are likely to be lethal.
Highly conserved genes are essential for the normal function of all organisms, from prokaryotes to eukaryotes. As a result, such genes are highly conserved and do not mutate easily. Conserved sequences are identical or similar sequences of DNA, RNA, or amino acids (proteins) that occur in different or the same species over generations in evolutionary biology and genetics.
These sequences exhibit very minor changes in composition over generations, and in some cases, no changes at all.
The following are common examples of conserved sequences:
Sequences related to translation and transcription that are found conserved in the genome at multiple locations.
Certain RNA components in ribosomes have been discovered to be highly conserved across species.
Other examples include TATA (repetitive regions) and homeoboxes, which have been found to be conserved in multiple bacteria species (involved in regulating embryonic development in a wide range of species).

Note:
The Conserved Domains database at NCBI contains a wealth of information on conserved sequences in various organisms and genomes. It identifies conserved sequences by using protein-specific scoring matrices.