Question
Biology Question on Digestive glands
Urea is produced in
kidneys
liver
nephrons
spleen
liver
Solution
Urea (also known as carbamide) is an organic compound of carbon, nitrogen, oxygen and hydrogen, with the formula CON2H4 or (NH2)2CO. The urea is formed in the livers of mammals in a cyclic pathway, from the break down of ammonia (a metabolic waste), which was initially named the Krebs-Henseleit cycle after its discoverers, and later became known simply as the urea cycle (also known as the ornithine cycle). In this cycle, amino groups donated by ammonia and L-aspartate are converted to urea, while L-omithine, citrulline, L-arginino-succinate , and L-arginine act as intermediates. Urea is essentially a waste product; it has no physiological function. It is dissolved in blood (in humans in a concentration of 2.5 - 7.5 mmol/litre) and excreted by the kidney in the urine. In addition, a small amount of urea is excreted (along with sodium chloride and water) in human sweat.