Question
Question: The ‘theory of opsonization ’, which explains the mechanism of destruction of pathogenic bacteria wa...
The ‘theory of opsonization ’, which explains the mechanism of destruction of pathogenic bacteria was given by
A. Wright and S.Douglas
B. Pasteur and Koch
C. Avery, Mac Cleod and McCarty
D. Von Behring
Solution
Opsonins is a type of protein. Opsonins are immunoglobulins of the G category (IgG) and are mostly accountable for the body's resistance to bacteria, viruses, and tumors.
Complete answer:
The term opsonization refers to the capability of antibodies and complement parts (as well as different proteins) to coat dangerous antigens which will then be recognized by antibodies or complement receptors on vegetative cell cells. Opsonization is the type of molecular mechanism whereby molecules, microbes, or apoptotic cells or chemicals are changed in order to possess stronger interactions of cell surface receptors with phagocytes and antibodies. This is the mechanism of distinguishing invasive particles (antigens) by the employment of specific proteins known as Opsonins. The Opsonins act as markers or tags that permit recognition by the system of the body. An antibody is an associate molecule that enhances bodily function by marking an associate degree substance for an immunologic response or marking dead cells for employment. The purpose of the bodily process is to create the antigens palatable to the protein or the vegetative cells.
-In 1903, British scientists A. Wright and S. Douglas gave the idea of a bodily process that explains the mechanism of destruction of microscopic pathogenic microorganisms.
-Koch and Pasteur are considered founders of medical bacteriology as they gave the germ theory.
-Oswald Avery, Colin Mac Cleod, and Maclyn McCarty showed that deoxyribonucleic acid (not proteins) will remodel the properties of cells, showing the chemical nature of genes. Avery, McLeod, and McCarty are known to identify deoxyribonucleic acid as the "transforming principle" while finding out about Streptococcus pneumoniae , a bacterium that will cause the respiratory disorder.
-Von Behring brought up antitoxin for diphtheria.
Hence, option A is the correct answer.
Note: Opsonization of pathogens will occur via antibodies or the complement system. The mechanism of opsonization is generally used by antibodies to inhibit and clear infection. Antibody-mediated body process by antibodies involves the coating of pathogens with antibodies so they're recognized and phagocytosed by innate immune cells.