Question

The technique called gamete intrafallopian transfer (GIFT) is recommended for those females
A: Who cannot produce an ovum
B: Who cannot retain the fetus inside the uterus
C: Whose cervical canal is too narrow to allow passage for the sperms
D: Who cannot provide a suitable environment for fertilization

Answer 1

Gamete intrafallopian transfer is an assisted reproductive technology. In this sperm and unfertilized oocytes are transferred into the fallopian tube and then fertilization takes place inside the body of the female.

Complete answer: Infertility is a failure to conceive within one or two years of regular unprotected coitus(copulation). Anovulation (no ovulation) in which there is no corpus luteum formation, many other types of infertility in females are luteal phase defect (decreased level of FSH or LH), defective growth of uterus and vagina, unfavorable endometrium for implantation (chronic endometritis (TB), Fibroid uterus), chronic cervicitis, elongation of the cervix, increased sperm phagocytosis by macrophages, early miscarriage, ectopic pregnancy, tubectomy. Asch and his colleagues were the first who discovered Gamete intrafallopian transfer. It was a more expensive and invasive procedure than In vitro fertilization, but its results are better than in vivo fertilization. In Gamete intrafallopian transfer both the unfertilized oocytes and sperm are transferred into the fallopian tubes. Eggs removed from a female's ovaries and sperm are placed in one of the fallopian tubes. After that fertilization takes place in vivo (inside the body of the female body). Normal fallopian tubes are required for gamete intrafallopian transfer. In GIFT also superovulation is done as in IVF. There is a 50 percent pregnancy rate per retrieval cycle. GIFT is basically used for infertile females who are ovulating and wish to avoid fertilization outside the body.

Hence, the correct option is (a).

Note: In gamete intrafallopian transfer instructions are the same as IVF (in-vivo fertilization) except the tubal factor. Zygote Intrafallopian transfer is closure to natural conception, the eggs are placed in the fallopian tubes rather directly in the uterus. GIFT fertilization takes place inside the body.