Question
Microbiology Question on Microbial Assay
The resistance to macrolide antibiotics by of gram positive organism is developed due to
A
Decreases uptake of antibiotics
B
Synthesis of esterase enzyme that hydrolyzes lactone ring of macrolide
C
Methylation of 50S subunit at the antibiotic binding site
D
Increased metabolism of antibiotic
Answer
Synthesis of esterase enzyme that hydrolyzes lactone ring of macrolide
Explanation
Solution
The correct option is (B): Synthesis of esterase enzyme that hydrolyzes lactone ring of macrolide