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Question

Biology Question on Human Excretory System

The principal nitrogenous excretory compound in humans is synthesised

A

in kidneys but eliminated mostly through liver

B

in kidneys as well as eliminated by kidneys

C

in liver and also eliminated by the same through bile

D

in the liver, but eliminated mostly through kidneys.

Answer

in the liver, but eliminated mostly through kidneys.

Explanation

Solution

The principle nitrogenous excretory compound in humans is urea. Urea is produced in a series of reactions (urea cycle) which take place in the mitochondrial matrix and cytosol of liver cells. Urea cycle (ornithine cycle) is the series of biochemical reactions that converts ammonia, which is highly toxic, and carbon dioxide to the much less toxic urea during the excretion of metabolic nitrogen derived from the deamination of excess amino acids. The urea is ultimately excreted in solution in urine.