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Question: The pK<sub>a</sub> of acetylsalicylic acid (aspirin) is 3.5 . The pH of gastric juice in human stoma...

The pKa of acetylsalicylic acid (aspirin) is 3.5 . The pH of gastric juice in human stomach is about 2-3 and pH in the small intestine is about 8. Aspirin will be.

A

Unionized in the small intestine and in the stomach

B

Completely ionized in the stomach and almost unionized in the small intestine.

C

Ionized in the stomach and almost unionized in the small intestine

D

Ionised in the small intestine and almost unionised in the stomach

Answer

Ionised in the small intestine and almost unionised in the stomach

Explanation

Solution

More ionized in basic medium and less ionized in acidic medium, common ion effect