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Question

Chemistry Question on Nucleic Acids

The moiety present at the 5' end of ribose sugar in a polynucleotide is

A

OH

B

CH2_2

C

Phosphate

D

Adenine

Answer

Phosphate

Explanation

Solution

A polynucleotide has a free phosphate moiety at 5'-end of ribose sugar, which is referred to as 5'-end of polynucleotide chain, and at the other end of the polymer the ribose has a free 3'-OH group which is referred to as 3'-end of the polynucleotide chain.