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Question

Biopharmaceutics and Pharmacokinetics Question on Bio-pharmaceutics

The loading dose (DL) of a drug is usually based on the:

A

Total body clearance of the drug

B

Percentage of drug bound to plasma proteins

C

Fraction of drug excreted unchanged in the urine

D

Apparent volume of distribution & desired drug concentration in plasma

Answer

Apparent volume of distribution & desired drug concentration in plasma

Explanation

Solution

The correct option is (D) :Apparent volume of distribution & desired drug concentration in plasma