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Question

Biology Question on Mendelian Disorders

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement :

A

Both are due to a quantitative defect in globin chain synthesis

B

Thalassemia is due to less synthesis of globin molecules

C

Sickel cell anemia is due to a quantitative problem of globin molecules

D

Both are due to a qualitive defect in globin chain synthesis

Answer

Thalassemia is due to less synthesis of globin molecules

Explanation

Solution

Thalassemia differs from sickle-cell anaemia in that
the former is a quantitative problem of synthesising too few globin molecules while the latter is a qualitative problem of synthesising an incorrectly functioning globin.