Question

TAB second booster dose is given at the age of
a. 2-3 years
b. 4-6 years
c. 10th year
d. 16th year

Answer 1

Booster dose is an extra dose given after the initial or primary dose, this dose is given by again reexposing the antigen to the body, so the immunity again starts increasing up to protective level, it is given mainly at the time where old immunity or memory cells start declining.

Complete answer:
- TAB is a typhoid vaccine and it contains suspensions of typhoid, paratyphoid a, paratyphoid b.
- Vaccine mainly contains the killed Salmonella typhi, where they contain not less than 1,000 million bacteria of S. Typhi Type 2 strain and it also contains 500 million each of Salmonella paratyphi A & B strains per human dose of 1 ml.
- This TAB vaccine is generally Preserved by 0.5%Phenol.
- The strain of bacteria used for a vaccine has a full complement of o H. and VI antigens.
- For this vaccine, the organisms are killed by heating at 56°C for one hour and by the addition of Phenol 1%.
- This TAB vaccine is initially given at the age of 6 years and the booster dose of the vaccine is given by the age of 16th year.

The TAB vaccine is mainly given the following conditions.
1. TAB is mainly used for the protection of persons where they are in direct contact with patients and carriers.
2. If the persons exposed by reason of their occupation (medical and Paramedical persons etc.)
3. In Medical Institutions and other public places where the appropriate hygienic condition can not be met.
4. In areas where there is a chance of high endemic incidence.

Hence, the correct answer is option (D).

Note: Parenteral and systemic vaccine administration has severe systemic and local adverse reactions, like fever, localized pain at the area of vaccine, and swelling at the site of injection, and it is contraindicated in the people who already have a history of systemic and local reactions.