Question

Sulphanilamide is a drug having a chemical name:
(A) p-aminobenzenesulfonamide
(B) m-aminobenzenesulphonamide
(C) o-aminobenzenesulfonamide
(D) None of these

Answer 1

Sulphanilamide is the antibacterial drug. As the name suggests it is a derivative of the amide functional group. It contains the Sulphur group and amide as the nucleus. The structure has the molecular formula of $\text{ }{{\text{C}}_{\text{6}}}{{\text{H}}_{\text{8}}}{{\text{N}}_{\text{2}}}{{\text{O}}_{\text{2}}}\text{ }$. We can say that the Sulphanilamide is a compound that contains the sulfonamide linkage to the benzene ring and $\text{ }-\text{N}{{\text{H}}_{\text{2}}}\text{ }$ at the $\text{ }{{4}^{\text{th}}}\text{ }$ position concerning it.

Complete step by step answer:
We can see the complete molecular structure of this compound from the following given diagram and the molecular formula for this compound is ${{\text{C}}_{\text{6}}}{{\text{H}}_{\text{8}}}{{\text{N}}_{\text{2}}}{{\text{O}}_{\text{2}}}$ which is the molar mass of 172 gram per mole.
We will derive the molar mass of this compound by adding the atomic masses of each of the elements present in the compound.

Here, we can see the structure of a benzene molecule connected to an amino group on one hand, and the other hand it is connected to the sulfonamide group.
This compound functions by competitively inhibiting enzyme metric reactions which involve para-amino benzoic acid or PABA.
Hence, we can determine its chemical name as p-aminobenzenesulfonamide.
So, the correct answer is “Option A”.

Mammals usually do not synthesize their Folic acid hence are unaffected by PABA inhibitors that selectively kill bacteria. An Austrian chemist named Paul Joseph Jacob Gelmo first prepared Sulphanilamide in 1908 as a part of his dissertation for a doctoral degree from Technische Hochschule in Vienna. This preparation method was patented in 1909. Sulfanilamide is a term that is used also to describe the family of molecules containing functional groups such as
-Furosemide
-Sulfadiazine
-Sulfamethoxazole
In the above-given points, Furosemide is a loop diuretic while sulfadiazine and Sulfamethoxazole are antibiotics.

Note: It should be known to us that Sulfanilamide was used in World War 2 by various Nations to reduce infection rates and selectively kill bacteria. The white Sulfanilamide powder was common in the first aid kits to treat intestinal infections as well. The sulpha drugs are derivatives of Sulfanilamide drug, this breakdown into the body to produce Sulphanilamide.