Question

Sickle cell anaemia is caused by substitution of

• A. Valine by glutamic acid at sixth position of $\alpha$ chain of Hb
• B. Valine by glutamic acid at sixth position of $\beta$-chain of Hb
• C. Glutamic acid by valine at sixth position of $\alpha$-chain of Hb
• D. Glutamic acid by valine at sixth position of $\beta$-chain of Hb

Answer 1

Answer: (D)

Glutamic acid by valine at sixth position of $\beta$-chain of Hb

Answer 2

Answer (d) Glutamic acid by valine at sixth position of $\beta$-chain of Hb