Question

Serum is
(a)Blood without blood cells
(b)Plasma without fibrinogen
(c)Blood without plasma
(d)Blood without RBC

Answer 1

The serum is the portion of the blood that does not contain coagulation factors. The clear liquid which can be isolated from clotted blood is serum. The plasma also includes antibodies and coagulation factors.

Complete answer:
The serum is the blood liquid and solute portion that does not play a role in coagulation. It can be characterized as blood plasma without fibrinogens. The serum is the portion of the blood that is neither a blood cell nor a clotting factor; it is the plasma of the blood that does not contain fibrinogens.
White blood cells (leukocytes), red blood cells (erythrocytes), platelets, or coagulation factors are not found in the serum.
The serum is analogous to interstitial fluid in which the proper functioning of muscles and nerves requires the correct composition of main ions acting as electrolytes. Proteins that help preserve pH and osmotic equilibrium while giving blood viscosity are other components in the serum; antibodies or specific proteins that are essential for protection against viruses and bacteria; lipids that are transported in the serum, including cholesterol; and various other substances, including nutrients, hormones, metabolic waste, and external substances.

Additional Information:
The liquid portion of blood, plasma, constitutes 55 percent of the total volume of blood. It can be segregated at high rotations of 3000 rpm or higher by artificially spinning or centrifuging the blood. The blood cells and platelets that makeup about 45% of the blood are extracted at the bottom of a specimen tube by centrifugal forces, leaving the plasma as the upper layer. Plasma consists of 90% water and various substances needed to sustain the pH of the body, osmotic load, and protect the body.
A blood sample is authorized to clot (coagulation) to acquire serum. In order to extract the clot and the blood cells, the sample is then centrifuged and the resulting liquid supernatant is serum.
So, the correct answer is, ‘Plasma without fibrinogen’.

Note: Serology is the study of serum. In various medical tests as well as blood typing, the serum is used. For several uses, calculating the concentration of different molecules may be helpful, such as assessing a drug candidate's therapeutic index in a clinical trial.