Question
Biology Question on biotechnology
Select the correctly matched pair.
A
Cosmid - Cannot be used in human genome project
B
BAC - 300-350 kb of foreign DNA
C
YAC - Can clone fragments upto 45kb in length only
D
Phagemid - An RNA based cloning vector carrying an origin of replication derived from adenovirus.
Answer
BAC - 300-350 kb of foreign DNA
Explanation
Solution
Bacterial artificial chromosome (BAC) vectors are based on natural, extra-chromosomal plasmid of E.coii. These vectors can accommodate upto 300-350 kb of foreign DNA and are also being used in genome sequencing project.