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Biology Question on the molecular basis of inheritance

Read the following statements and choose the set of correct statements:

  1. Euchromatin is loosely packed chromatin
  2. Heterochromatin is transcriptionally active
  3. Histone octamer is wrapped by negatively charged DNA in nucleosome
  4. Histones are rich in lysine and arginine
  5. A typical nucleosome contains 400 bp of DNA helix

Choose the correct answer from the options given below:

A

(b), (d), (e) Only

B

(a), (c), (d) Only

C

(b), (e) Only

D

(a), (c), (e) Only

Answer

(a), (c), (d) Only

Explanation

Solution

Heterochromatin refers to regions of DNA that are densely packed with histone proteins, rendering them transcriptionally inactive. This is in contrast to euchromatin. Each nucleosome contains approximately 200 base pairs of DNA helix.